8 days old

Senior Scientist

West Chester, PA 19380

Company Info

Teva is a global pharmaceutical leader and the world's largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world's largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we've built a promising pipeline centered around our core therapeutic areas. We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!

Job Description

As the Senior Scientist you will be required to have the knowledge, experience, and skills to lead and support cell-based assay development, ELISA development and sample testing of biologics within the Analytical Sciences, Bioassays and Biosciences Group.  Specific areas of focus are: cell-based assay and ELISA method development, including transient and stable cell line creation using transfection/ viral transduction, method qualification to support product characterization and lot stability, method technology transfer to internal and external sites, SOP and work instruction authorship and review. You will engage, support, and review work conducted at CROs.  

 

You will be responsible for authorship and review of technical reports and protocols. As the Senior Scientist you should possess a strong fundamental knowledge of cell function and have a background in supporting methods including flow cytometry and cell sorting, profiling cell responses to ligands, RNAi, antibody effector function assessment aand western blot.  Strong knowledge and background with a variety of biological in-vitro systems is required (cell migration, proliferation, cell signaling, differentiation, transporters). Familiarity with GMP bioassay processes is desirable.

 

The ability to solve problems and manage multiple activities is a must.  Other areas of support will be needed for conducting lab investigations in area of expertise, regulatory filing support, and the ability to oversee external work occurring at CRO. Work will include assay design, troubleshooting, data evaluation, project planning and timelines and coordinating studies with other technical groups.  Presentation of experimental outcomes to coworkers or management is expected. The position will promote a culture of quality, compliance and continuous improvement.

 

Other duties:

  • Establish cell based assays and ELISA methods to support product characterization, product stability testing and process development 
  • Identify and/or create cell lines containing drug targets as a critical reagent for potency assays
  • Mentor and train  junior staff
  • Support product method validation and transfers as applicable.
  • Identify, write, revise, manage and implement standard operating procedures, work instructions, standard practices, protocols and reports.
  • Drafts sections of INDs and BLAs as applicable.
  • Develop strategy and approach for special studies as applicable.
  • Support QC lab investigations.  
  • Lead and/or participate method validation/transfer for the developed assays to QC or third parties
  • Evaluate new and emerging analytical technologies

Qualifications

What you will bring to the role:

  • PhD in life sciences or related field
  • Minimum 5 years of experience in cell based assay and ELISA development
  • Minimum 1 year of experience in direct management or matrix management responsibilities

Function

Research & Development

Sub Function

Drug Analysis and Formulation

Reports To

Principal Fellow

Already Working @TEVA?

If you are a current Teva employee, please apply using the internal career site available on "Employee Central". By doing so, your application will be treated with priority. You will also be able to see opportunities that are open exclusively to Teva employees. Use the following link to search and apply: Internal Career Site

The internal career site is available from your home network as well. If you have trouble accessing your EC account, please contact your local HR/IT partner.

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. We are committed to a diverse and inclusive workplace for all. If you are contacted for a job opportunity, please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience.  

Categories

Posted: 2021-04-27 Expires: 2021-05-27

Join us at the forefront of pharmaceutical research and production. With state-of-the-art facilities, highly skilled colleagues, and a high-powered organizational culture, Teva offers you countless possibilities to make a real difference in people's lives and add value to your career.

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Senior Scientist

Teva Pharmaceuticals
West Chester, PA 19380

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