16 days old

Biological Researcher

West Chester, PA 19380
Company Info
Teva is a global pharmaceutical leader and the world's largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world's largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we've built a promising pipeline centered around our core therapeutic areas. We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!
Job Description


The Research Associate (RA) will work in the department of Upstream Development and Operations at Teva within Biologics CMC. The RA will participate in cell culture process development for early and late stage development projects.

They will work in a collaborative setting with other process development staff.Theywill be expected to independently operate bench scale (3-10L) and pilot scale (<200L) bioreactors, including proactive planning, and successful execution of complex experimental protocols for process development, characterization, scale-up and technology assessment.

The RA will also be expected to independently operate high throughput automation equipment (e.g TECAN, Ambr 250, Ambr15). Additional duties will include record keeping for cell culture and analytics, data analysis, and presentations of technical data to internal teams,detailed documentation and organization ofall of the analytical results obtained and develop experimental plan and execute cell culture and/or harvest studies in laboratory either individually or in teams.

Other duties:

  • Perform routine cell culture maintenance & seed culture expansion to support bioreactor runs.
  • Perform process development/characterization and scale-up experiments with CHO cells expressing monoclonal antibody in shaker flasks and multiple scale (Ambr15, Ambr 250, 10, 50, 100 and 200L) bioreactors.
  • Perform equipment set-up, sterilization, daily operation, sampling and in-process analytical testing (cell count, viability, gases, metabolites, titer etc).
  • Maintain laboratory equipment, coordinate calibration, and manage raw material stocks and supplies. Troubleshoot high throughput automation (TECAN, Ambr 15, Ambr 250) equipment related issues in collaboration with relevant internal groups.
  • Maintain a compliant laboratory operation in accordance with development protocols, internal procedures and policies. Record experiments in lab notebooks and perform needed data analysis. Document work in technical reports when needed.
  • Conduct data analysis and present data at internal team meetings on cell culture experiments periodically.
Qualifications

 

Minimum Qualifications:

  • Bachelor's degree in Biology, Biochemistry, Chemical Engineering or other scientific related field of study
  • Minimum 2 years of experience in cell culture process development for antibody or other biologic products
  • Minimum 2 years of experience with mammalian cell culture


Preferred Qualifications:

  • 5+ years of experience in the biopharmaceutical/biotechnology industry.
  • Experience in operation of perfusion systems and/or high throughput  Ambr15, 250 system
  • Hands-on experience with in-process analytical testing  such as cell counters and instruments for metabolite analysis 
  • Hands-on experience using lab automation (e.g. TECAN) for sample handling/purification etc.
Function
Research & Development
Sub Function
Biological Research
Reports To
In process of validation
Already Working @TEVA?

If you are a current Teva employee, please apply using the internal career site available on "Employee Central". By doing so, your application will be treated with priority. You will also be able to see opportunities that are open exclusively to Teva employees. Use the following link to search and apply: Internal Career Site

The internal career site is available from your home network as well. If you have trouble accessing your EC account, please contact your local HR/IT partner.

Categories

Posted: 2020-10-05 Expires: 2020-11-20

Join us at the forefront of pharmaceutical research and production. With state-of-the-art facilities, highly skilled colleagues, and a high-powered organizational culture, Teva offers you countless possibilities to make a real difference in people's lives and add value to your career.

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Biological Researcher

Teva Pharmaceuticals
West Chester, PA 19380

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